As a result, your levels might be higher when you wake-up. My Wife also takes a small amount injectable insulin twice daily. This is when chemicals known as ketones are released in the blood. Internal causes for high blood sugar include when your liver produces too much glucose, your body makes too little insulin, or your body can't effectively use insulin. This is helpful for the random spikes of high blood sugar, and not for the standard high glucose. It contributes to many biological functions including the breaking down of sugars to extract energy. But it's a great time to learn about the disease, and its treatment. You should talk to your healthcare team about whether intramuscular injections are a good idea during hyperglycemic episodes. High blood sugar often occurs slowly over a number of hours to days. In a previous study, it was found that high blood sugar is less common in those who drank more water. Harrell however recommends that you test your blood sugar at the very least once a day.